Pre-implantation genetic aneuploidy screening (PGAS)

Pre-implantation genetic aneuploidy screening (PGAS) is an  increasingly popular procedure with older women. PGAS aims to improve the chance of having a healthy live birth in the following patient groups:

• Women aged 40 and above

• Couples who have undergone at least three fresh IVF cycles without success

• Women who suffer from recurrent miscarriages.

It is known that chromosomal abnormal (aneuploid) embryos contribute to poor IVF outcome. PGAS enables the analysis of specific chromosomes to be performed on a single cell removed from an embryo of 5 cells or more. Following this analysis only the embryos that test normal for the chromosomes analysed are selected for transfer to the uterus. By not transferring chromosomal abnormal embryos, PGAS can increase the chances of a successful outcome.